The tall, green-eyed brunette received wide recognition for her performance as the mute, mysterious Greek resistance figher "Anna" in the 1961 film The Guns of Navarone, which starred Gregory Peck. Miss Scala's successful career began to deteriorate as a result of a growing alcohol dependency and she was eventually let go from her studio contract. Her marriage to stockbroker Donald Burnett ended in divorce.
Scala made frequent appearances on American television shows during the 1960s. Shows in which she appeared include Alfred Hitchcock Presents (1960-1961), Convoy, The Rogues, Voyage to the Bottom of the Sea, Twelve O'Clock High (1965), Tarzan (NBC series) (1967), and It Takes a Thief (1969).